Lysine could also be dosed from 1 to 3 g each day to forestall or deal with herpes simplex infections, reserving the higher dosages for breakouts. Patients with liver and kidney impairment should keep away from supplementation with lysine. Use of calcium dietary supplements with lysine could also be associated with elevated absorption and lowered elimination of calcium. Aminoglycoside toxicity may be enhanced in patients taking lysine supplementation.

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